MP Biomedicals™ Laminin, MP Biomedicals™

Description

Supports cell adhesion, proliferation and differentiation. Laminin, MP Biomedicals, an extracellular matrix glycoprotein, is the major non-collagenous component of basal lamina and an integral component of structural scaffolding in animal tissue. It is us

Laminin, an extracellular matrix (ECM) multidomain trimeric glycoprotein, was initially isolated from mouse Engelbreth-Holm-Swarm (EHS) tumor (laminin-1). Laminins associate with type IV collagen via entactin and perlecan and bind to cell membranes through integrin receptors, dystrogylcan glycoprotein complex and Lutheran blood group glycoprotein. Laminin has active domains for collagen binding, cell adhesion, heparin binding, and neurite outgrowth fragment.

Laminin (approximately 1 × 10⁶ daltons) is a cell adhesion factor.

• Useful in culturing cells on glass or plastic
• Significantly facilitates the culture of epithelial and endothelial cells
• Supports growth and differentiation of many cell types, including epithelial, endothelial, neural, muscle, and liver cells

Specifications

• Formulation: Supplied in 0.05M TRIS; 0.15M NaCl; pH 7.4
• Name: Laminin
• Quantity: 1 mg
• Source: Mouse EHS Sarcoma
• Storage Requirements: Store at -70°C.
• Form: Frozen
• Purity or Quality Grade: 95+% pure by SDS-PAGE

Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov