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Apexbio Technology LLC Lamotrigine 84057-84-1 1g
Supplier: Apexbio Technology LLC B22491000
Lamotrigine (CAS 84057-84-1) is a small molecule anticonvulsant that acts primarily as a voltage-gated sodium channel blocker stabilizing neuronal membranes and inhibiting repetitive neuronal firing Research indicates that lamotrigine inhibits serotonin (5-HT) uptake with reported IC50 values of 240 M in human platelets and 474 M in rat brain synaptosomes These dual actions on sodium channels and 5-HT transport underline its utility in studies investigating the modulation of excitatory neurotransmission and synaptic function in neurological and psychiatric conditions
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