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Apexbio Technology LLC Lansoprazole sodium 226904-00-3 1g
Supplier: Apexbio Technology LLC B12901000
Lansoprazole sodium is a small-molecule inhibitor targeting gastric H /K -ATPase and several human cytochrome P450 (CYP) isoforms including CYP2C9 and CYP2C19 It is designed to inhibit acid secretion by selectively modulating H /K -ATPase activity in parietal cells and to modulate CYP-mediated metabolism pathways Lansoprazole sodium exerts its biological activity primarily through inhibition of its targets In human liver microsome studies it inhibits CYP2C9 and CYP2C19 with Ki values of approximately 21 M and 1 M respectively its inhibitory effect on CYP2D6 and CYP3A4 is weaker with IC values above 200 M Based on these pharmacological properties Lansoprazole sodium holds research potential in the investigation of gastric acid secretion disorders and drug drug interaction profiles involving CYP-mediated metabolism
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