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Cayman Chemical Lapachone 10mg
Supplier: Cayman Chemical 1502110 MG
A quinone which inhibits topoisomerase I at 25 μM and transglutaminase (IC50 = 5 μM); reduced to β-lapachone hydroquinone by NQO1, generating ROS during its reversion to β-lapachone; sensitizes cancer cells to radiation, suppresses NF-κB activation, and drives apoptosis
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