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β-Lapachone, Tocris Bioscience™

Catalog No. 129310
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Quantity:
10 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

DNA topoisomerase I inhibitor

DNA topoisomerase I inhibitor. Exhibits a different inhibitory mechanism to camptothecin (Cat. No. 1100). Induces apoptosis in a variety of cell lines, including prostate cancer and promyelocytic leukemia cells; blocks the cell cycle in G0/G1. Also has effects on DNA topoisomerase II, NF-κB, AP-1, and JNK.

Chemical Identifiers

CAS 4707-32-8
Molecular Formula C15H14O3
Molecular Weight (g/mol) 242.27
MDL Number MFCD01712233
InChI Key QZPQTZZNNJUOLS-UHFFFAOYSA-N
Synonym beta-lapachone, lapachone, beta, .beta.-lapachone, lapachone, 2,2-dimethyl-3,4-dihydro-2h-benzo h chromene-5,6-dione, unii-6n4fa2qq6a, 3,4-dihydro-2,2-dimethyl-2h-naphtho 1,2-b pyran-5,6-dione, 2h-naphtho 1,2-b pyran-5,6-dione, 3,4-dihydro-2,2-dimethyl, 6n4fa2qq6a
PubChem CID 3885
ChEBI CHEBI:10429
IUPAC Name 2,2-dimethyl-2H,3H,4H,5H,6H-naphtho[1,2-b]pyran-5,6-dione
SMILES CC1(C)CCC2=C(O1)C1=CC=CC=C1C(=O)C2=O

Specifications

Quantity 10 mg
Formula Weight 242.27
Percent Purity >98%
Chemical Name or Material β-Lapachone

Safety and Handling

Recommended Storage Store at +4°C
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