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Apexbio Technology LLC LAQ824 (NVP-LAQ824,Dacinostat) 404951-53-7 200mg
Supplier: Apexbio Technology LLC A4103200
LAQ824 (NVP-LAQ824 Dacinostat CAS 404951-53-7) is a synthetic derivative of 4-aminomethylcinnamic hydroxamic acid that functions as a histone deacetylase (HDAC) inhibitor It exhibits potent HDAC inhibition with an IC50 of 0 03 M LAQ824 has demonstrated the ability to inhibit proliferation across a range of human cancer cell lines including colorectal (H1299 HCT116) breast (MDA435 SKBR-3 BT-474 MB-468) prostate (DU145 PC3) and non-small cell lung (A549) cancer models with IC50 values below 1 M Additionally it induces apoptosis in breast cancer cells and suppresses multiple myeloma cell growth in a time- and dose-dependent manner LAQ824 is widely utilized in cancer research to study epigenetic regulation and evaluate HDAC inhibitor-based therapeutic strategies
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