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Medchemexpress LLC Larsucosterol (trimethylamine) | 97.0% | 509.32 | 100 MG
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Supplier:  Medchemexpress LLC HY139576B100MG

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Larsucosterol (trimethylamine) is a cholesterol metabolite and a potent liver X receptor (LXR) antagonist. It acts as an endogenous regulator, decreasing lipogenesis and inhibiting cholesterol biosynthesis by reducing mRNA levels and blocking SREBP-1 activation.

  • Inhibits cholesterol biosynthesis by decreasing HMG-CoA reductase mRNA levels.
  • Inhibits HMG-CoA reductase expression via SREBP1 activation and expression in hepatocytes.
  • Increases cell proliferation and decreases apoptosis in macrophages.
  • Inhibits activation of liver oxysterol receptor LXRα in macrophages.

Catalog No. 50-003-50406


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