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Medchemexpress LLC Larsucosterol (trimethylamine) | 97.0% | 509.32 | 25 MG

Supplier: Medchemexpress LLC 25MGHY139576B
Larsucosterol (trimethylamine) is a cholesterol metabolite that functions as a potent liver X receptor (LXR) antagonist. This endogenous regulator decreases lipogenesis and inhibits cholesterol biosynthesis by reducing mRNA levels and inhibiting the activation of SREBP-1.
- Potent liver X receptor (LXR) antagonist
- Decreases lipogenesis
- Inhibits cholesterol biosynthesis
- Reduces mRNA levels of cholesterol biosynthesis enzymes
- Inhibits activation of SREBP-1
- Increases cell proliferation in macrophages
- Decreases apoptosis in macrophages
- Reduces serum lipid levels in NAFLD models
- Protects liver from injury by suppressing hepatic inflammation
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