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Apexbio Technology LLC Lasofoxifene (tartrate) 190791-29-8 25mg
Supplier: Apexbio Technology LLC C563725
Lasofoxifene tartrate (CAS 190791-29-8) is a small-molecule selective estrogen receptor modulator (SERM) targeting estrogen receptor-alpha (ER- ) and acting as a selective inverse agonist at the cannabinoid receptor subtype CB2 It is designed to modulate estrogen receptor signaling in a tissue-dependent manner thereby regulating estrogen-related biological pathways Lasofoxifene tartrate exerts its biological activity through dual estrogen agonist antagonist actions depending on tissue context In preclinical studies using ovariectomized rat models Lasofoxifene tartrate prevents estrogen deficiency-associated bone loss reduces serum cholesterol and body mass without inducing uterine hypertrophy Based on these pharmacological properties Lasofoxifene tartrate holds research potential in the management of osteoporosis breast cancer and cardiovascular health in postmenopausal women
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