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Cayman Chemical Latrunculin A Inhibitors
Supplier: Cayman Chemical 1001063050 UG
An actin disruption agent; sequesters G-actin and prevents F-actin assembly; binds monomeric actin with 1:1 stoichiometry and can be used to block actin polymerization both in vitro (Kd = 0.2 μM) and in cells (0.5 μM, 30 min); causes depolymerization of tumor cell cytoskeleton within ten minutes at 1-10 μM; suppresses actin synthesis at 10 μM; blocks dexamethasone-induced changes in actin cytoskeleton
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