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Medchemexpress LLC Lazertinib (mesylate) | 2247995-37-3 | 99.9% | 650.75 | 10 MG
SDP

Catalog No. 5000344469
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Lazertinib mesylate is a potent, selective, CNS-penetrant, orally available, and irreversible EGFR tyrosine kinase inhibitor. It exhibits high selectivity for activating (EGFRm) and T790M resistance mutations. Lazertinib mesylate inhibits phosphorylation of EGFR, AKT, and ERK, leading to apoptosis and suppression of tumor growth in mouse H1975-luc brain metastasis xenograft models. It can be used in the study of non-small cell lung cancer.

  • Potent, selective, CNS-penetrant, orally available, and irreversible EGFR tyrosine kinase inhibitor.
  • High selectivity for activating (EGFRm) and T790M resistance mutations.
  • Inhibits phosphorylation of EGFR, AKT, and ERK.
  • Leads to apoptosis and suppression of tumor growth in mouse H1975-luc brain metastasis xenograft models.
  • Can be used in the study of non-small cell lung cancer.

Catalog No. 50-003-44469 Supplier Medchemexpress LLC Supplier No. HY109061B10MG
May include imposed supplier surcharges.
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Lazertinib mesylate is a potent, selective, CNS-penetrant, orally available, and irreversible EGFR tyrosine kinase inhibitor. It exhibits high selectivity for activating (EGFRm) and T790M resistance mutations. Lazertinib mesylate inhibits phosphorylation of EGFR, AKT, and ERK, leading to apoptosis and suppression of tumor growth in mouse H1975-luc brain metastasis xenograft models. It can be used in the study of non-small cell lung cancer.

  • Potent, selective, CNS-penetrant, orally available, and irreversible EGFR tyrosine kinase inhibitor.
  • High selectivity for activating (EGFRm) and T790M resistance mutations.
  • Inhibits phosphorylation of EGFR, AKT, and ERK.
  • Leads to apoptosis and suppression of tumor growth in mouse H1975-luc brain metastasis xenograft models.
  • Can be used in the study of non-small cell lung cancer.

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