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Medchemexpress LLC Lazertinib mesylate | 2247995-37-3 | 99.9% | 650.75 | 25 MG
SDP

Catalog No. 5000347237
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Lazertinib mesylate is a potent, selective, CNS-penetrant, orally available and irreversible EGFR tyrosine kinase inhibitor, exhibiting high selectivity for activating (EGFRm) and T790M resistance mutations. It inhibits phosphorylation of EGFR, AKT and ERK, leading to apoptosis and suppression of tumor growth in mouse H1975-luc brain metastasis xenograft models. Lazertinib mesylate can be used in the study of non-small cell lung cancer.

  • Potent, selective, CNS-penetrant, orally available, and irreversible EGFR tyrosine kinase inhibitor.
  • High selectivity for activating (EGFRm) and T790M resistance mutations.
  • Inhibits phosphorylation of EGFR, AKT, and ERK.
  • Leads to apoptosis and suppression of tumor growth in mouse H1975-luc brain metastasis xenograft models.
  • Applicable in the study of non-small cell lung cancer.
  • IC50 & Target: EGFRT790M.

Catalog No. 50-003-47237 Supplier Medchemexpress LLC Supplier No. 25MGHY109061B
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Lazertinib mesylate is a potent, selective, CNS-penetrant, orally available and irreversible EGFR tyrosine kinase inhibitor, exhibiting high selectivity for activating (EGFRm) and T790M resistance mutations. It inhibits phosphorylation of EGFR, AKT and ERK, leading to apoptosis and suppression of tumor growth in mouse H1975-luc brain metastasis xenograft models. Lazertinib mesylate can be used in the study of non-small cell lung cancer.

  • Potent, selective, CNS-penetrant, orally available, and irreversible EGFR tyrosine kinase inhibitor.
  • High selectivity for activating (EGFRm) and T790M resistance mutations.
  • Inhibits phosphorylation of EGFR, AKT, and ERK.
  • Leads to apoptosis and suppression of tumor growth in mouse H1975-luc brain metastasis xenograft models.
  • Applicable in the study of non-small cell lung cancer.
  • IC50 & Target: EGFRT790M.

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