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Cayman Chemical LCysteInsulfInIc ACDhydr 100mg

Supplier: Cayman Chemical 29597100 MG
An excitatory amino acid and mGluR agonist; increases intracellular inositol phosphate levels in CHO cells expressing mGluR1, mGluR5, or mGluR8 (EC50s = 120, 30, and 110 μM, respectively) and inhibits forskolin-induced cAMP production in CHO cells expressing mGluR2 or mGluR6 and hamster kidney cells expressing mGluR4 (EC50s = 100, 100, and 2,000 μM, respectively); selectively binds to mGluR1α (Ki = 3,510 nM) over adrenergic, dopamine, histamine, muscarinic, nicotinic, or serotonin receptors (Kis = >10,000 nM for all); decreases mean arterial blood pressure and heart rate in rats when microinjected into the NTS at 1 mM); can be formed via oxidation of L-cysteine by ROS
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