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Medchemexpress LLC LDC4297 hydrochloride | 2319747-14-1 | 98.2% | 1 ML

Supplier: Medchemexpress LLC HY12653A10MM/1ML
LDC4297 hydrochloride is a selective inhibitor of CDK7 with an IC50 value of 0.13 nM. It inhibits human cytomegalovirus (HCMV) replication with an EC50 value of 24.5 nM. This product shows broad antiviral activities against Herpesviridae, Adenoviridae, Poxviridae, Retroviridae, and Orthomyxoviridae, with EC50 values ranging from 0.02-1.21 μM. It can be used for infection research.
- Dose-dependently inhibits HCMV replication with an EC50 of 24.5 nM
- Shows anti-proliferative activity in primary human fibroblast cultures with a GI50 of 4.5 μM
- Exhibits anti-HCMV activity by interfering with virus-induced Rb phosphorylation
- Demonstrates broad antiviral activities against various viruses including HCMV, GPCMV, MCMV, HIV-1, and Influenza A virus
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