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Medchemexpress LLC LDC4297 hydrochloride | 2319747-14-1 | 98.2% | 10 MG
Supplier: Medchemexpress LLC HY12653A10MG
LDC4297 hydrochloride is a selective inhibitor of CDK7 with an IC50 value of 0.13 nM. It demonstrates broad antiviral activities against various viruses, including human cytomegalovirus (HCMV) replication with an EC50 value of 24.5 nM. Its antiviral spectrum extends to Herpesviridae, Adenoviridae, Poxviridae, Retroviridae, and Orthomyxoviridae, with EC50 values ranging from 0.02-1.21 μM. This compound is suitable for research related to infection.
- Selective inhibitor of CDK7
- Inhibits human cytomegalovirus (HCMV) replication
- Shows broad antiviral activities against multiple virus families
- Exhibits anti-proliferative activity against human fibroblast primary cultures
- Interferes with virus-induced Rb phosphorylation
- Demonstrates promising pharmacokinetic properties in CD1 mice
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