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Cayman Chemical LDE225phosphate 10mg
Supplier: Cayman Chemical 1626310 MG
A Smo antagonist (IC50s = 1.3 and 2.5 nM for mouse and human Smo, respectively); inhibits Gli1 mRNA expression and prevents tumor growth in an orthotopic Ptch+/- p53-/- medulloblastoma mouse allograft model at 20 mg/kg per day
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