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Medchemexpress LLC LDLR protein, Human (HEK293, His) | ≥ 95.0% | 99-140 kDa | 250 UG
Supplier: Medchemexpress LLC 250UGHYP70235
LDLR Protein plays a pivotal role in cholesterol homeostasis by binding to low-density lipoprotein (LDL) and mediating its cellular uptake through endocytosis. The clustering of receptor-ligand complexes into clathrin-coated pits is essential for internalization. In the context of microbial infection, LDLR also acts as a receptor for the hepatitis C virus in hepatocytes, highlighting its diverse roles in both cholesterol metabolism and the cellular response to viral infections. This product is a recombinant human-derived LDLR protein, expressed by HEK293, with a C-6*His labeled tag.
- Purity of ≥ 95%
- Molecular weight of approximately 99-140 kDa
- Derived from human species
- Expressed in HEK293 cells
- Features a C-6*His labeled tag
- Pivotal in cholesterol homeostasis
- Mediates cellular uptake of low-density lipoprotein (LDL)
- Acts as a receptor for hepatitis C virus
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