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TARGETMOL CHEMICALS INC LDN-193189 2HCl 25MG
SDP

Supplier:  TARGETMOL CHEMICALS INC T3534825MG

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Also available in 1 mL, 5 mg, 10 mg, 50 mg, 100 mg, 500 mg and bulk. Please contact Fisher for quotes. LDN-193189 2HCl (DM-3189 2HCl) is a selective BMP signaling inhibitor that inhibits ALK1,ALK2,ALK3 and ALK6, showing IC50s of 0.8 nM, 0.8 nM, 5.3 nM, and 16.7 nM, respectively, in kinase assays.LDN-193189 2HCl inhibited the transcriptional activity of BMP type I receptors in C2C12 cells, with IC50s of 5 nM and 30 nM, respectively. LDN-193189 2HCl inhibited the transcriptional activity of BMP type I receptors ALK2 and ALK3 in C2C12 cells, with IC50s of 5 nM and 30 nM, respectively, and was 200-fold more selective for BMP than for TGF-beta. Purity 99.78%

Catalog No. 50-287-6642


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