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Medchemexpress LLC LDN-209929 dihydrochloride | 1784281-97-5 | 98.3% | 405.77 | 100 MG
SDP

Catalog No. 5000343601
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LDN-209929 dihydrochloride is a potent and selective haspin kinase inhibitor (IC50=55 nM) with 180-fold selectivity verses DYRK2 (IC50=9.9 μM). It is an optimized analogue of LDN-192960. This compound targets haspin kinase, a serine/threonine kinase crucial in mitosis, and also inhibits DYRKs, a family of kinases involved in various cellular processes.

  • Potent and selective haspin kinase inhibitor
  • IC50 of 55 nM for haspin kinase
  • 180-fold selectivity versus DYRK2
  • IC50 of 9.9 μM for DYRK2
  • Optimized analogue of LDN-192960
  • Suitable for research in metabolic or endocrine disease, cancer, lipid metabolism, and obesity
  • Targets protein tyrosine kinase/RTK and haspin kinase pathways

Catalog No. 50-003-43601 Supplier Medchemexpress LLC Supplier No. HY11032010MG
May include imposed supplier surcharges.
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LDN-209929 dihydrochloride is a potent and selective haspin kinase inhibitor (IC50=55 nM) with 180-fold selectivity verses DYRK2 (IC50=9.9 μM). It is an optimized analogue of LDN-192960. This compound targets haspin kinase, a serine/threonine kinase crucial in mitosis, and also inhibits DYRKs, a family of kinases involved in various cellular processes.

  • Potent and selective haspin kinase inhibitor
  • IC50 of 55 nM for haspin kinase
  • 180-fold selectivity versus DYRK2
  • IC50 of 9.9 μM for DYRK2
  • Optimized analogue of LDN-192960
  • Suitable for research in metabolic or endocrine disease, cancer, lipid metabolism, and obesity
  • Targets protein tyrosine kinase/RTK and haspin kinase pathways

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