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Medchemexpress LLC LDN-91946 | 439946-22-2 | 98.0% | 1 ML
SDP

Catalog No. 5000340630
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LDN-91946 is a potent, selective, and uncompetitive ubiquitin C-terminal hydrolase-L1 (UCH-L1) inhibitor with a Ki app of 2.8 μM. It is intended for research use only. The compound is inactive against UCH-L3 at 20 μM and shows no activity against TGase 2, Papain, and Caspase-3 at 40 μM. It also exhibits no cytotoxicity in serum-starved Neuro 2A (N2A) cells at concentrations up to 0.1 mM.

  • Potent, selective, and uncompetitive UCH-L1 inhibitor
  • Ki app of 2.8 μM (UCH-L1)
  • Inactive against UCH-L3 at 20 μM
  • No activity against TGase 2, Papain, and Caspase-3 at 40 μM
  • No cytotoxicity in serum-starved Neuro 2A (N2A) cells up to 0.1 mM

Catalog No. 50-003-40630 Supplier Medchemexpress LLC Supplier No. HY1298910MM/1ML
May include imposed supplier surcharges.
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LDN-91946 is a potent, selective, and uncompetitive ubiquitin C-terminal hydrolase-L1 (UCH-L1) inhibitor with a Ki app of 2.8 μM. It is intended for research use only. The compound is inactive against UCH-L3 at 20 μM and shows no activity against TGase 2, Papain, and Caspase-3 at 40 μM. It also exhibits no cytotoxicity in serum-starved Neuro 2A (N2A) cells at concentrations up to 0.1 mM.

  • Potent, selective, and uncompetitive UCH-L1 inhibitor
  • Ki app of 2.8 μM (UCH-L1)
  • Inactive against UCH-L3 at 20 μM
  • No activity against TGase 2, Papain, and Caspase-3 at 40 μM
  • No cytotoxicity in serum-starved Neuro 2A (N2A) cells up to 0.1 mM

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