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Medchemexpress LLC Lefamulin (acetate) | 1350636-82-6 | 99.7% | 567.78 | 25 MG
Supplier: Medchemexpress LLC 25MGHY16908A
Lefamulin (BC-3781) acetate is an orally active antibiotic. It inhibits protein synthesis by binding to the peptidyl transferase center of the 50S bacterial ribosome. This product also exhibits anti-inflammatory activity and is used in the research of bacterial infections, such as bacterial pneumonia.
- Inhibitory activity against *C. trachomatis*, *N. gonorrhoeae*, and *M. genitalium* in vitro.
- Potent activity against *M. pneumoniae* strains with MIC values of ≤0.008 μg/mL.
- Shows anti-inflammatory effect on LPS-induced lung neutrophilia mouse models in vivo.
- Demonstrates antibacterial effect in *S. pneumoniae* or *S. aureus* challenged lung infection mice.
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