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Enzo Life Sciences Leflunomide (50mg). CAS: 75706-12-6
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Supplier:  Enzo Life Sciences ALX430095M050

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Immunosuppressive drug that inhibits T and B cell responses in vivo. Inhibitor of tyrosine phosphorylation (tyrosine kinase inhibitor), of dihydroorotate dehydrogenase, an enzyme for de novo pyrimidine synthesis, of TNF-dependent NF-κB activation, and of COX-2. The physiological activity of leflunomide is attributed mainly to its metabolite A77 1726 (ALX-430-096). Alternative name: HWA486, 5-Methylisoxazole-4-(4-trifluoromethylcarboxanilide), N-(4-Trifluoromethylphenyl)-5-methylisoxazol-4-carboxamide. Purity: ≥98.5% (HPLC). Solubility: Soluble in DMSO or methanol. Long Term Storage: +4°C.

Catalog No. 50-200-9198


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