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Medchemexpress LLC Leflunomide | 75706-12-6 | 99.8% | C12H9F3N2O2 | 1 ML
Supplier: Medchemexpress LLC HYB008310MM/1ML
Leflunomide is a pyrimidine synthesis inhibitor that acts by inhibiting dihydroorotate dehydrogenase (DHODH), functioning as a disease-modifying antirheumatic agent. It is an immunomodulatory drug that prevents the expansion of activated and autoimmune lymphocytes by interfering with cell cycle progression due to inadequate rUMP production and by utilizing mechanisms involving p53. This product is for research use only.
- Inhibits dihydroorotate dehydrogenase (DHODH)
- Functions as a disease-modifying antirheumatic agent
- Inhibits proliferation of mononuclear and T-cells
- Inhibits several protein tyrosine kinases
- Prevents expansion of activated and autoimmune lymphocytes
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