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Apexbio Technology LLC Lenalidomide hemihydrate 847871-99-2 1g
Supplier: Apexbio Technology LLC B11881000
Lenalidomide hemihydrate (CAS 847871-99-2) is a small-molecule immunomodulator targeting the E3 ubiquitin ligase CRBN It is designed to induce selective ubiquitination and degradation of the lymphoid transcription factors IKZF1 and IKZF3 thereby modulating immune cell signaling pathways Lenalidomide hemihydrate exerts its biological activity primarily by inhibiting TNF- secretion with an IC50 value of approximately 13 nM Its mechanism of action also includes altering cytokine production and cellular interactions within the tumor microenvironment Based on these pharmacological properties Lenalidomide hemihydrate holds research potential in the investigation of inflammatory pathways immune response modulation and antitumor mechanisms particularly in hematological malignancies and inflammatory diseases
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