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Selleck Chemical LLC Lenalidomide10mg
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Supplier:  Selleck Chemical LLC S102910MG

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Lenalidomide (CC-5013) is aTNF-? secretion inhibitor withIC50 of 13 nM in PBMCs. Lenalidomide (CC-5013) is a ligand ofubiquitin E3 ligase cereblon (CRBN), and it causes selective ubiquitination and degradation of two lymphoid transcription factors, IKZF1 and IKZF3, by the CRBN-CRL4 ubiquitin ligase. Lenalidomide promotescleaved caspase-3 expression and inhibitVEGF expression and inducesapoptosis. *For Research & Development use only.  Product is not intended for drug, household, or human consumption.

Catalog No. 50-217-3055


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