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Medchemexpress LLC Lenvatinib (mesylate) | 857890-39-2 | 99.7% | 522.96 | 25 MG
SDP

Catalog No. 5000347036
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Lenvatinib mesylate is an oral, multi-targeted tyrosine kinase inhibitor. It inhibits vascular endothelial growth factor receptors (VEGFR1-3), fibroblast growth factor receptors (FGFR1-4), platelet-derived growth factor receptor (PDGFR), KIT, and RET. The compound demonstrates potent antitumor activities.

  • Inhibits VEGFR2 with an IC50 of 4 nM
  • Inhibits VEGFR3 with an IC50 of 5.2 nM
  • Inhibits VEGFR1 with an IC50 of 22 nM
  • Inhibits PDGFRα with an IC50 of 51 nM
  • Inhibits PDGFRβ with an IC50 of 39 nM
  • Inhibits FGFR1 with an IC50 of 46 nM
  • Inhibits KIT with an IC50 of 100 nM
  • Significantly inhibits local tumor growth and metastasis in preclinical models

Catalog No. 50-003-47036 Supplier Medchemexpress LLC Supplier No. 25MGHY10981A
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Lenvatinib mesylate is an oral, multi-targeted tyrosine kinase inhibitor. It inhibits vascular endothelial growth factor receptors (VEGFR1-3), fibroblast growth factor receptors (FGFR1-4), platelet-derived growth factor receptor (PDGFR), KIT, and RET. The compound demonstrates potent antitumor activities.

  • Inhibits VEGFR2 with an IC50 of 4 nM
  • Inhibits VEGFR3 with an IC50 of 5.2 nM
  • Inhibits VEGFR1 with an IC50 of 22 nM
  • Inhibits PDGFRα with an IC50 of 51 nM
  • Inhibits PDGFRβ with an IC50 of 39 nM
  • Inhibits FGFR1 with an IC50 of 46 nM
  • Inhibits KIT with an IC50 of 100 nM
  • Significantly inhibits local tumor growth and metastasis in preclinical models

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