Leptomycin B, 98%, 1mM soln. in ethanol, Thermo Scientific Chemicals

Description

 

Potent, specific inhibitor of nuclear export signal (NES)-dependent protein export from the nucleus

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

• Potent, specific inhibitor of nuclear export signal (NES)-dependent protein export from the nucleus

Specifications

Chemical Identifiers

• CAS: 87081-35-4
• Molecular Formula: C33H48O6
• Molecular Weight (g/mol): 540.741
• MDL Number: MFCD06795848
• InChI Key: YACHGFWEQXFSBS-BVPMNVLFSA-N
• PubChem CID: 121232734
• IUPAC Name: (2E,5S,6R,7S,9R,10E,12E,15R,16Z,18E)-17-ethyl-6-hydroxy-3,5,7,9,11,15-hexamethyl-19-[(2R,3R)-3-methyl-6-oxo-2,3-dihydropyran-2-yl]-8-oxononadeca-2,10,12,16,18-pentaenoic acid
• SMILES: CCC(=CC(C)CC=CC(=CC(C)C(=O)C(C)C(C(C)CC(=CC(=O)O)C)O)C)C=CC1C(C=CC(=O)O1)C

• Type: Leptomycin B
• Physical Form: Liquid
• Odor: Alcohol-like
• Color: Colorless
• Concentration: 1mM soln. in ethanol
• Quantity: 100 μg
• Flash Point: 11°C (52°F)
• UN Number: UN1993
• Merck Index: 14,5444
• Formula Weight: 540.73
• Percent Purity: ≥99%
• Chemical Name or Material: Leptomycin B

Safety and Handling

Hazard Category	H225-H319
Hazard Statement	GHS H Statement H225 Highly flammable liquid and vapor.
Precautionary Statement	P210-P233-P240-P241-P242-P243-P264b-P280-P303+P361+P353-P305+P351+P338-P370+P378q-P501c
DOTInformation	Transport Hazard Class: 3; Packaging Group: II; Proper Shipping Name: FLAMMABLE LIQUIDS, N.O.S.
TSCA	No
storageNote1	-30° to -10°C
Recommended Storage	Store at -20°C

SDS

For Manufacturing and Laboratory Use. Not for beverage use