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Cayman Chemical LeukadherIn 1 10mg
Supplier: Cayman Chemical 1485510 MG
An allosteric activator of CD11b/CD18; increases K562 cell adhesion to fibrinogen (EC50 = 4 µM); reduces rolling velocity of leukocytes, decreasing the number of leukocytes recruited to injured tissue; anti-inflammatory in a zebrafish tailfin injury model and a mouse model of nephritis; competitively inhibits YopH (Ki = 1.94 µM) and anthrax lethal factor metalloproteinase (IC50 = 6 µM)
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