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Cayman Chemical Leukotriene B4-3-aminopropyla

Supplier: Cayman Chemical 2011450 UG

A histamine H2 receptor antagonist (Ki 0 6 M) also acts as an inverse agonist inhibiting basal cAMP production in CHO cells expressing recombinant H2 receptors (IC50 1 2 M) inhibits histamine-induced acid secretion from isolated bullfrog gastric mucosa (IC50 16 M) inhibits histamine-induced gastric acid secretion in gastric fistulae and Heidenhain pouches in dogs (ED50 1 88 mol/kg p o ) reduces tumor growth and neovascularization in a CMT93 colon cancer mouse syngeneic model at 20 mg/kg per day
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