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Cayman Chemical Leukotriene D4, 73836-78-9, 50 µg
SDP

Supplier:  Cayman Chemical 2031050

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LTD4 is one of the constituents of slow-reacting substance of anaphylaxis (SRS-A) produced by the metabolism of LTC4 by γ-glutamyl transpeptidase.{541,589} It is the first CysLT metabolite of LTC4. Like LTC4, LTD4-induced bronchoconstriction and enhanced vascular permeability contribute to the pathogenesis of asthma and acute hypersensitivity.{4157,482} LTD4 is equipotent to LTC4 in its biological activities, except that LTD4 is nearly 100-fold more effective in the contraction of peripheral airway smooth muscle.{396,392}

Catalog No. NC1332552


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