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Medchemexpress LLC Levocabastine hydrochloride | 79547-78-7 | 99.4% | C26H30ClFN2O2 | 1 MG
Supplier: Medchemexpress LLC HY14277A1MG
Levocabastine hydrochloride is a potent and selective histamine H1-receptor antagonist. It also acts as a selective, high-affinity neurotensin receptor subtype 2 (NTR2) antagonist and functions as a VLA-4 antagonist, interfering with conjunctival eosinophil infiltration in allergic conjunctivitis (AC). It is a white to off-white solid with a molecular weight of 456.98.
- Potent and selective histamine H1-receptor antagonist.
- Selective, high-affinity neurotensin receptor subtype 2 (NTR2) antagonist.
- Functions as a VLA-4 antagonist.
- Interferes with conjunctival eosinophil infiltration in allergic conjunctivitis.
- Inhibits α4β1 integrin/VCAM-1-mediated cell adhesion.
- Inhibits virus-induced airway hyperresponsiveness in guinea pigs.
- Prevents conjunctival elevation of VLA-4 and eosinophil infiltration.
- Appears as a white to off-white solid.
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