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Apexbio Technology LLC Levofloxacin 100986-85-4 5g

Supplier: Apexbio Technology LLC B19595000
Levofloxacin (CAS 100986-85-4) is a small-molecule inhibitor targeting bacterial DNA gyrase (topoisomerase II) It modulates DNA supercoiling thereby regulating DNA replication and transcription in bacteria Levofloxacin exerts its biological activity primarily through stabilization of the DNA enzyme cleavage intermediate interfering with DNA replication and causing bacterial cell death In in vitro studies Levofloxacin demonstrates antibacterial inhibitory activity with IC50 values typically ranging from approximately 0 5 g/mL to 4 g/mL depending on bacterial species and experimental conditions Based on these pharmacological properties Levofloxacin holds research potential in studies involving bacterial susceptibility profiling and the development of antibiotic resistance
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