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Cayman Chemical LevofloxacIn N-oxIde 25mg

Supplier: Cayman Chemical 2717725 MG

An inhibitor of the protein-protein interaction between MDM2 and p53 (IC50 5 nM in a p53-MDM2 HTRF binding assay) inhibits the proliferation of SJSA-1 RKO and HCT116 cells (average IC50 20 nM) increases apoptosis in SJSA-1 cells in a concentration-dependent manner reduces tumor growth and induces tumor regression in an SJSA-1 osteosarcoma mouse xenograft model at 1 56 and 6 25 mg/kg respectively
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