LiChropur™ N-tert-Butyldimethylsilyl-N-methyltrifluoroacetamide, MilliporeSigma™ Supelco™

Description

N-tert-Butyldimethylsilyl-N-methyltrifluoroacetamide is a silylating reagent which replaces the active hydrogen with tert-Butyldimethylsilyl group. The tert-Butyldimethylsilyl derivatives are found to be more resistant to hydrolysis and stable compared to trimethylsilyl (TMS) derivatives.

• Suitable for GC-MS analysis since it produces mass spectra, which can be easily interpreted
• It is widely used for the silylation of different alcohols, thiols, phenols, carboxylic acids, amines, and amides

Specifications

Chemical Identifiers

• CAS: 77377-52-7
• Molecular Formula: C9H18F3NOSi
• Molecular Weight (g/mol): 241.33
• MDL Number: MFCD00009671
• InChI Key: NEJIKZHUEMMAEF-UHFFFAOYSA-N
• Synonym: MTBSTFA
• IUPAC Name: N-(butyldimethylsilyl)-2,2,2-trifluoro-N-methylacetamide
• SMILES: CCCC[Si](C)(C)N(C)C(=O)C(F)(F)F

• Density: 1.036 g/mL (at 25°C (literature))
• Flash Point: 45°C (Closed Cup)
• Linear Formula: CF3CON(CH3)Si(CH3)2 C(CH3)3
• UN Number: UN 1993 C 3 / PGIII
• Boiling Point: 172°C to 175°C (literature)
• Quantity: 10 mL
• Formula Weight: 241.33
• Percent Purity: ≥99% (GC)
• Grade: GC Derivatization

Safety and Handling

Hazard Category	H226 - H315 - H319 - H335
Recommended Storage	2°C to 8°C

LiChropur is a trademark of Merck KGaA, Darmstadt, Germany