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LiChropur™ N-tert-Butyldimethylsilyl-N-methyltrifluoroacetamide, MilliporeSigma™ Supelco™

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10 mL
77377-52-7
C9H18F3NOSi
241.33
MFCD00009671
NEJIKZHUEMMAEF-UHFFFAOYSA-N
MTBSTFA
N-(butyldimethylsilyl)-2,2,2-trifluoro-N-methylacetamide
CCCC[Si](C)(C)N(C)C(=O)C(F)(F)F
77377-52-7
C9H18F3NOSi
241.33
MFCD00009671
NEJIKZHUEMMAEF-UHFFFAOYSA-N
MTBSTFA
N-(butyldimethylsilyl)-2,2,2-trifluoro-N-methylacetamide
CCCC[Si](C)(C)N(C)C(=O)C(F)(F)F

Description

N-tert-Butyldimethylsilyl-N-methyltrifluoroacetamide is a silylating reagent which replaces the active hydrogen with tert-Butyldimethylsilyl group. The tert-Butyldimethylsilyl derivatives are found to be more resistant to hydrolysis and stable compared to trimethylsilyl (TMS) derivatives.

  • Suitable for GC-MS analysis since it produces mass spectra, which can be easily interpreted
  • It is widely used for the silylation of different alcohols, thiols, phenols, carboxylic acids, amines, and amides
Linear Formula CF3CON(CH3)Si(CH3)2 C(CH3)3
UN Number UN 1993 C 3 / PGIII
Formula Weight 241.33
Percent Purity ≥99% (GC)
Grade For GC Derivatization
Density 1.036 g/mL (at 25°C (literature))
Boiling Point 172°C to 175°C (literature)
Quantity 10 mL
Flash Point 45°C (Closed Cup)

Safety and Handling

H226 - H315 - H319 - H335

Recommended Storage : 2°C to 8°C

LiChropur is a trademark of Merck KGaA, Darmstadt, Germany