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Medchemexpress LLC Lidocaine hydrochloride | 73-78-9 | 99.8% | 5 G
Supplier: Medchemexpress LLC HYB0185A5G
Lidocaine hydrochloride (Lignocaine hydrochloride) is an amide derivative that inhibits sodium channels. It decreases the growth, migration, and invasion of gastric carcinoma cells by up-regulating miR-145 expression and inactivating the MEK/ERK and NF-κB signaling pathways. It is used to treat ventricular arrhythmia and is an effective tumor-inhibitor.
- Decreases cell proliferation
- Inhibits cell viability
- Increases the apoptotic cell rate
- Down-regulates Cyclin D1 and up-regulates p21 expression
- Causes completely reversible tail nerve block in rats
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