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Cayman Chemical LIgustrazInhydrochlorIde 50mg
Supplier: Cayman Chemical 2965850 MG
A compound with diverse biological activities; inhibits hydrogen peroxide-induced decreases in cell viability and the levels of SOD and GPX and increases in ROS and MDA levels in HUVECs at 100 and 150 μg/ml;) inhibits PGE2 production induced by LPS and IFN-γ in primary rat glia at 50 and 100 μM; reduces infarct volume, cortical edema, and cortical PGE2 levels in a rat model of transient focal cerebral ischemia induced by common carotid artery and middle cerebral artery occlusion at 20 mg/kg; inhibits the proliferation of MG-63, Saos-2, and U2OS osteosarcoma cells (IC50s = 10.3, 24.7, and 54.7 mg/ml, respectively) in vitro; reduces tumor growth in an MG-63 mouse xenograft model at 100 mg/kg every other day
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