Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. 5000058170

Genscript Corporation LILRA4/CD85gBiotin His Av

Catalog No. 5000058170
Encompass

LILRA4 also known as ILT7 and CD85g is an approximately 60-70 kDa variably glycosylated transmembrane protein that regulates immune cell activation Mature human LILRA4 consists of a 423 amino acid (aa) extracellular domain (ECD) with four immunoglobulin-like domains a 21 aa transmembrane segment and a 32 aa cytoplasmic domain LILRA4 function coreceptor to limit the innate immune responses to viral infections signaling occurs via FCER1G (PubMed 16735691 PubMed 19564354) Down-regulates the production of IFNA1 IFNA2 IFNA4 IFNB1 and TNF by plasmacytoid dendritic cells that have been exposed to influenza virus or cytidine-phosphate-guanosine (CpG) dinucleotides indicating it functions as negative regulator of TLR7 and TLR9 signaling cascades

Catalog No. 50-000-58170 Supplier Genscript Corporation Supplier No. Z04538100
May include imposed supplier surcharges.
Add to Cart
Add to Cart

missing translation for 'validMainframeMsg'

LILRA4 also known as ILT7 and CD85g is an approximately 60-70 kDa variably glycosylated transmembrane protein that regulates immune cell activation Mature human LILRA4 consists of a 423 amino acid (aa) extracellular domain (ECD) with four immunoglobulin-like domains a 21 aa transmembrane segment and a 32 aa cytoplasmic domain LILRA4 function coreceptor to limit the innate immune responses to viral infections signaling occurs via FCER1G (PubMed 16735691 PubMed 19564354) Down-regulates the production of IFNA1 IFNA2 IFNA4 IFNB1 and TNF by plasmacytoid dendritic cells that have been exposed to influenza virus or cytidine-phosphate-guanosine (CpG) dinucleotides indicating it functions as negative regulator of TLR7 and TLR9 signaling cascades

Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.