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Genscript Corporation LILRB4/CD85k/ILT3Biotin His
Supplier: Genscript Corporation Z04546100
LILRB4 also known as CD85k and LIR-5 ILT3 is an approximately 60 kDa transmembrane glycoprotein that negatively regulates immune cell activation Mature human ILT3 consists of a 238 amino acid (aa) extracellular domain with two Ig-like domains a 21 aa transmembrane segment and a 168 aa cytoplasmic domain with 3 immunoreceptor tyrosine-based inhibitory motifs (ITIM) LILRB4 is receptor for class I MHC antigens Recognizes a broad spectrum of HLA-A HLA-B HLA-C and HLA-G alleles
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