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AdipoGen Linagliptin
Supplier: AdipoGen AGCR13618M010
Chemical. CAS 668270-12-0. Formula C25H28N8O2. MW 472.5. Antidiabetic agent. Highly potent and selective competitive inhibitor of dipeptidyl-peptidase 4 DPP4 DPP IV CD26, an enzyme that degrades, glucagon-like peptide-1 GLP-1 and glucose-dependent insulinotropic polypeptide GIP. Prevents the inactivation of endogenous GLP-1 and GIP. Shown to restore beta cell function and survival in human isolated islets through GLP-1 stabilization. Improves insulin sensitivity. Anti-inflammatory compound.
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