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Lincomycin hydrochloride

Catalog No. AAJ6125103
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Quantity:
1 g
5 g
25 g

Lincomycin hydrochloride, CAS # 859-18-7, is a compound showing antibacterial activity against a wide variety of bacteria, including Staphylococcal, Streptococcal, and Bacteroides fragilis infections. It also shows inhibitory activity against protein synthesis. | CAS: 859-18-7 | C18H35ClN2O6S | 442.996 g/mol

Lincomycin hydrochloride is used to study the inhibition of protein synthesis, bacterial antibiotic resistance and protein and surfactant binding. It has been used in the treatment of Staphylococcal, Streptococcal, and Bacterioides fragilis infections.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

  • Lincomycin hydrochloride is a lincosamide compound with antibacterial activity originally identified in the actinomycete, Streptomyces lincolnensis, with activity against gram-positive cocci and anaerobic bacteria
  • Lincomycin inhibits bacterial protein synthesis by forming cross-links within the peptidyl transferase loop region of the 23S rRNA

Application

  • Lincomycin hydrochloride is commonly used to study the inhibition of protein synthesis, bacterial antibiotic resistance, and protein and surfactant binding
  • It has been used against Staphylococcal, Streptococcal, and Bacteroides fragilis species
  • It is protective against the development of mastitis in a mouse model of acute mastitis induced by S. aureus
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 859-18-7
Molecular Formula C18H35ClN2O6S
Molecular Weight (g/mol) 442.996
MDL Number MFCD00058237
InChI Key POUMFISTNHIPTI-OXVORJCQSA-N
PubChem CID 124080936
IUPAC Name (2R,4R)-N-[(1R,2R)-2-hydroxy-1-[(2S,3R,4S,5R,6S)-3,4,5-trihydroxy-6-methylsulfanyloxan-2-yl]propyl]-1-methyl-4-propylpyrrolidine-2-carboxamide;hydrochloride
SMILES CCCC1CC(N(C1)C)C(=O)NC(C2C(C(C(C(O2)SC)O)O)O)C(C)O.Cl

Specifications

Type Lincomycin Hydrochloride
Physical Form Crystalline Powder
Color White
Quantity 1 g
Beilstein 4171650
Solubility Information Soluble in water
Formula Weight 443
Chemical Name or Material Lincomycin hydrochloride
missing translation for 'healthHazard1' H315-H319-H335
missing translation for 'healthHazard2' GHS H Statement
H315-H319-H335
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.
missing translation for 'healthHazard3' P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P501c
EINECSNumber 212-726-7
RTECSNumber RH6315000
TSCA No
Recommended Storage Keep cold

RUO – Research Use Only

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