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Selleck Chemical LLCSupplier Diversity Partner Linifanib (ABT-869) 5mg 796967-16-3 AL39324,RG3635  DFS Item

Manufacturer:  Selleck Chemical LLCSupplier Diversity Partner S10035MG

Linifanib (ABT-869, AL39324, RG3635) is a novel, potent ATP-competitive VEGFR/PDGFR inhibitor for KDR, CSF-1R, Flt-1/3 and PDGFRβ with IC50 of 4 nM, 3 nM, 3 nM/4 nM and 66 nM respectively, mostly effective in mutant kinase-dependent cancer cells (i.e. FLT3). Linifanib (ABT-869) induces autophagy and apoptosis. Phase 3.

Catalog No. 50-687-2


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