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Cayman Chemical Lipid Droplets Assay Dye Extr
Supplier: Cayman Chemical 60004630 ML
A Y-secretase modulator selectively inhibits the production of AB42 in CHO cells expressing wild-type APP (IC50 9.8 nM) over Notch cleavage to NICD (IC50 >15.8 UM) decreases brain levels of AB42 in rats at 10 and 40 mg/kg decreases CSF levels of AB40 and AB42 and increases levels of AB38 and AB39 without affecting total AB CSF levels in dogs at 20 mg/kg
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