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Cayman Chemical LIpId HTO12 50mg

Supplier: Cayman Chemical 4120250 MG
An ionizable cationic lipid (pKa = 6.432); has been used in combination with other lipids in the formation of LNPs for the delivery of mRNA in vitro and in vivo; LNPs containing lipid HTO12 and encapsulating adenine base editor mRNA targeting Pcsk9 reduce hepatic Pcsk9 levels in mice at a reduced ionizable lipid/total lipids-to-mRNA ratio than LNPs containing SM-102
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