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Cayman Chemical LIpId III-45 50mg
Supplier: Cayman Chemical 3924350 MG
An ionizable cationic lipid; has been used in the generation of LNPs for the delivery of mRNA in vivo; LNPs containing lipid III-45 and encapsulating a luciferase mRNA reporter accumulate in liver and adipose tissue in mice; LNPs containing lipid III-45 have been used to deliver an mRNA sequence encoding an antibody targeting claudin-18.2 to mice and reduce tumor volume in an MDA-MB-231 mouse xenograft model
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