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Cayman Chemical LIpId OA2hydrochlorIde 50mg
Supplier: Cayman Chemical 3798750 MG
An ionizable cationic lipid; has been used in the generation of single-component LNPs for the delivery of siRNA; LNPs containing lipid OA2 and siRNA targeting Socs1 decrease Socs1 expression by ~50% in isolated mouse BMDCs; vaccination with ovalbumin-induced isolated mouse BMDCs transfected with LNPs composed of lipid OA2 and Socs1-targeting siRNA increases survival and decreases tumor volume in a B16-OVA murine melanoma model
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