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Cayman Chemical LIpoxygenIn 10mg

Supplier: Cayman Chemical 2631010 MG
A 5-LO inhibitor (IC50 = 5 µM for A23187-stimulated 5-LO product synthesis in isolated human granulocytes); inhibits hedgehog-dependent signaling in Shh-LIGHT2 cells and TGF-β-, activin A-, BMP-, or Wnt-dependent signaling in HEK293T cells (IC50s = 9.3, 3.2, 8.2, 9.6, and 3.7 µM, respectively, in luciferase reporter assays); increases TnnT levels in BMP4- and CHIR99021-stimulated human iPSCs
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