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Apexbio Technology LLC Liranaftate 88678-31-3 10mg
Supplier: Apexbio Technology LLC B178010
Liranaftate (CAS 88678-31-3) is a small-molecule inhibitor targeting fungal squalene epoxidase It is designed to inhibit the conversion of squalene to ergosterol thereby disrupting fungal cell membrane integrity and impeding cell viability Liranaftate exerts its biological activity through inhibition of squalene epoxidase and downregulation of interleukin-8 (IL-8) expression induced by fungal elements In relevant experimental studies Liranaftate demonstrates potent inhibitory activity against fungal squalene epoxidase with an IC50 ranging from 2 to 10 nM Based on these pharmacological properties Liranaftate holds research potential in dermatological studies investigating fungal skin infections and inflammatory signaling pathways
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