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Sigma Aldrich Lithium Diisopropylamide

Catalog No. 24661125G Shop All MilliporeSigma Sigma Organic Chemistry Products
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MilliporeSigma Sigma Organics products encompass a wide range of quality reagents, solvents, catalysts, and building blocks for organic synthesis. From benchtop discovery to process development and scale-up, Sigma Organics solutions are built to meet the needs of synthetic chemists.

Lithium diisopropylamide (LDA) is a hindered non-nucleophilic strong base that abstracts hydrogen from active carbon. It can be prepared from diisopropylamine and butyllithium in the presence of tetrahydrofuran.Lithium diisopropylamide can be used for the generation of carbanion or enolate anions from carbonyl group-containing compounds.It can also be used as a base in: The direct alkylation and acylation of ketones. The aldol condensation reaction. +a-Selenation reaction. The synthesis of +a, +a- unsaturated carbonyl compounds from carbonyl compounds. The alkylation of acids, esters, amides, and nitriles. The initiation of anionic polymerization.

Specifications

CAS 4111-54-0
Density 0.864 g/mL at 25°C
Molecular Formula C6H14LiN
Linear Formula [(CH3)2CH]2NLi
MDL Number MFCD00064449
Quantity 25 g
Synonym LDA
Molecular Weight (g/mol) 107.12 g/mol
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