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Cayman Chemical LIxIsenatIdeacetate 50mg

Supplier: Cayman Chemical 3973950 MG

An ionizable cationic lipid has been used in the generation of LNPs LNPs containing cKK-E15 and encapsulating Cre mRNA and induce the expression of Cre in Kupffer cells endothelial cells and hepatocytes in Ai14 mice translation of mRNA delivered to the liver by LNPs containing cKK-E15 is inhibited by LPS in Ai14 mice but not by low-grade chronic liver inflammation in a B16/F10 murine model of cancer-induced inflammation the delivery of LNPs containing cKK-E15 is not dependent upon ApoE or Ldlr expression in mice
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