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Medchemexpress LLC LL-37 amide TFA | 597562-32-8 | 99.3% | 4492.28 (free base) | 1 MG
Supplier: Medchemexpress LLC HYP4744A1MG
LL-37 amide TFA is a selective agonist of formyl peptide receptor-like FPRL1. It inhibits periodontal pathogens and exerts bactericidal effects by activating FPRL1-mediated immune cell chemotaxis and disrupting bacterial cell membrane integrity. It also regulates inflammatory responses by inhibiting factors like TNF-α and promotes angiogenesis. Amidation enhances its stability and reduces serum inhibition, making it useful in research for infection-related diseases, periodontal disease, deep tissue injuries, and wound healing.
- Improved stability and resistance to enzymatic degradation.
- Exhibits broad-spectrum bactericidal activity against Gram-positive and Gram-negative bacteria.
- Accelerates wound healing and bacterial clearance in Staphylococcus aureus skin infection models.
- Safe concentration range for eukaryotic cells is 0.1-10 μM.
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